ASTM D4626 Practice for Calculation of Gas Chromatographic Response Factors
1. Scope
1.1 This practice covers a procedure for calculating gas chromatographic response factors. It is applicable to chromatographic data obtained from a gaseous mixture or from any mixture of compounds that is normally liquid at room temperature and pressure or solids, or both, that will form a solution with liquids. It is not intended to be applied to those compounds that react in the chromatograph or are not quantitatively eluted. Normal C6 through C11 paraffins have been chosen as model compounds for demonstration purposes.
1.2 The values stated in SI units are to be regarded as the standard. The values stated in inch-pound units are for information only.
1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
2. Referenced Documents
2.1 ASTM Standards:
D2268 Test Method for Analysis of High-Purity n-Heptane and Isooctane by Capillary Gas Chromatography
D2427 Test Method for Determination of C2 through C5 Hydrocarbons in Gasolines by Gas Chromatography
D2804 Test Method for Purity of Methyl Ethyl Ketone By Gas Chromatography
D2998 Test Method for Polyhydric Alcohols in Alkyd Resins (Withdrawn 2004)
D3329 Test Method for Purity of Methyl Isobutyl Ketone by Gas Chromatography
D3362 Test Method for Purity of Acrylate Esters by Gas Chromatography (Withdrawn 2011)
D3465 Test Method for Purity of Monomeric Plasticizers by Gas Chromatography
D3545 Test Method for Alcohol Content and Purity of Acetate Esters by Gas Chromatography
D3695 Test Method for Volatile Alcohols in Water by Direct Aqueous-Injection Gas Chromatography
D4307 Practice for Preparation of Liquid Blends for Use as Analytical Standards
E260 Practice for Packed Column Gas Chromatography
3. Terminology
3.1 Definitions of Terms Specific to This Standard:
3.1.1 response factor (R) - a constant of proportionality used to convert the observed chromatographic response of specific compounds to either mass or volume percent composition. The observed response may be measured as peak areas or peak heights. Depending on the calculation formula, the response factor (R) is applied by either multiplying or dividing the observed response by the determined factor.
3.1.2 In this practice, the response factors determined are multiplying factors.
